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ANTIHISTAMINES: Desloratadine: Deslor
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Deslor
Presentation

Deslor Tablet: Each film-coated tablet contains Desloratadine INN 5 mg.Deslor Syrup: Each 5 ml syrup contains Desloratadine INN 2.5 mg.

Composition

Deslor (Desloratadine), the major, active metabolite of Loratadine, is anon-sedating, long acting tricyclic histamine antagonist with selective H1-receptorhistamine antagonist activity. Desloratadine also inhibits histamine release from humanmast cell.

Indications

Allergic rhinitis: Deslor is indicated for the relief of the nasaland non-nasal symptoms of allergic rhinitis (Seasonal and perennial). Chronic IdiopathicUrticaria: Deslor is indicated for symptomatic relief of pruritus, reduction in the numberof hives, and size of hives in patients with chronic idiopathic urticaria.

Dosage Administration

Adults and children 12 years of age and over: DeslorTablets: one tablet once daily. Deslor Syrup: 2 teaspoonful (10 ml) once daily.Children 6 to 11 years of age: Deslor Syrup: 1 teaspoonful (5 ml) once dailyChildren 1 to 5 years of age: Deslor Syrup: 1/2 teaspoonful (2.5 ml) once daily.Children 6 to 11 months of age: Deslor Syrup: 1/2 teaspoonful once daily.In adult patients with liver or renal impairment: A starting dose of one 5 mg tablet everyother day is recommended based on pharmacokinetic data.

Contraindications

Desloratadine is contraindicated in patient having hypersensitivity tothis medication or to any of its ingredients

Precaution

Antihistamines should be used with caution in hepatic diseases and dosereduction may be necessary in renal impairment. Caution may be required in epilepsy.Children and the elderly are more susceptible to side effects.

Use in pregnancy & Lactation

There is no experience of the use of Desloratadineduring pregnancy. Antihistamines present in milk although not known to be harmful.

Drug Interaction

No clinically important drug interactions have been reported

Side Effects

Adverse effects of Desloratadine are mild and transient in nature. Theseinclude dry mouth, headache and fatigue.

Packaging

Deslor Tablet: Box containing 10 X 10 tablets in blister pack.Deslor Syrup: Bottle containing 60 ml syrup.

Storage

Store in a cool and dry place. Keep away from light and out of children\'s reach

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