Preparation
Ketorin tablet : Each tablet contains Ketorolac Tromethamine USP 10 mg
Ketorin 30 Injection : Each 1 ml ampoule contains Ketorolac Tromethamine USP 30 mg.
Indication
Ketorin (Ketorolac) is indicated for the short-term management of moderate to severe pain. A beneficial effect has been shown in acute pain, in renal colic and in cancer pain but the major indication is for post-operative pain.
Contraindication
Ketorolac is contraindicated in the following situations: Patients previously sensitive to Ketorolac or Aspirin or other NSAIDs - Patients with active or suspected peptic or duodenal ulcer or who have GI or other bleeding disorders. - In severe heart failure and renal or hepatic insufficiency.
Side Effect
The major side effects are gastrointestinal like dyspepsia, abdominal pain, nausea, fluid retention, peptic ulceration, pancreatitis, palpitation, bradycardia, purpura etc. Flatulence, gastritis, constipation, vomiting etc may also occur.
Precaution
Ketorin (Ketorolac) should be used with caution in patients sufferingfrom GI disease and history of peptic ulceration, cerebrovascularbleeding, ulcerative colitis, cardiac decompensation, hypertension, renaland hepatic impairment. Dose should be reduced in elderly.
Ketorolac is contraindicated in the later stages of pregnancy and should only be used earlier in the pregnancy if there are compelling reasons. Because Ketorolac is distributed in milk, it should not be used during lactation.
Drug Interaction
Drug interactions may occur with Methotrexate, Diuretics.Antihypertensive drug, ACE inhibitors and Warfarin.
Presentation
Ketorin tablet : Box containing 2 x 10 Tablets in blister pack.Ketorin-30
Injection : Box containing 1 ampoule in blister pack.